The following searches will identify important statin safety issues. Use the Lipid Lowering template to help.
| Search Name | Search Location | Search Returns | Notes |
| ? Statin Safety 1.0 – Any statin – potential contraindicated interaction # | CDRC Quality – Lipids | Patients on repeat statin and another medication that appears to be contraindicated | Review patient medication to ensure safety |
| ? Statin Safety 1.1 – Simvastatin – ! MHRA ! Any potential contraindicated interaction # | CDRC Quality – Lipids | (Subset of 1.0 above) Patients on simvastatin with a contraindicated medication in line with the MHRA warning | Review record https://www.gov.uk/drug-safety-update/simvastatin-updated-advice-on-drug-interactions |
| ? Statin Safety 2.0 – Any statin – caution, potential interaction # | CDRC Quality – Lipids | Patients on repeat statin and another medication where caution is recommended | Review patient medication to ensure safety |
| ? Statin Safety 3.0 – Any statin – consider dose in view of eGFR # | CDRC Quality – Lipids | Patients on repeat statin whose renal function indicates that dose alteration MAY be needed | Review patient medication to ensure safety |
Additional safety support is available from the Lipid Lowering Safety Check and Lipid Lowering – Statin Safety – Clarithro/erythro protocols (activation at units or CCGs required).